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Effect of Dietary Corn Oil Supplementation on Equine Gastric Fluid Acid, Sodium, and Prostaglandin E2 Content before and during Pentagastrin Infusion
Brief content of the article
The effect of corn oil (approximately 60% [wt/vol] linoleic acid) dietary supplementation on various components of equine gastric secretion was studied by use of a repeated-measures experimental design. The authors observed that during the diet supplemented with corn oil, the ponies had, under basal and pentagastrin-stimulated conditions, significantly decreased acid output and significantly increased PGE2 and sodium outputs compared to those measured before corn oil supplementation. The authors concluded that corn oil supplementation may be an effective and inexpensive way to increase the protective properties of equine glandular gastric mucosa. This could be particularly helpful in reducing the chances of ulceration associated with nonsteroidal anti-inflammatory drug (NSAID) administration. A full abstract may be obtained from http://apt.allenpress.com/aptonline/?request=get-abstract&issn=0891-6640&volume=018&issue=04&page=0545
Keywords: gastric secretion; stomach; ulcers; EGUS.
Cargile J.L., Burrow, J.A., Kim, I., Cohen, N.D. and Merritt A.M. 2004. Effect of Dietary Corn Oil Supplementation on Equine Gastric Fluid Acid, Sodium, and Prostaglandin E2 Content before and during Pentagastrin Infusion. J. Vet. Intern. Med. 18: 545-549.
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