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Validation of diagnostic tests for determination of magnesium status in horses with reduced magnesium intake.
Brief content of the article
The researchers evaluated the diagnostic value of serum concentrations of total magnesium (Mg) and ionized magnesium, concentrations of magnesium in muscle, intracellular Mg concentrations, urinary Mg excretion, Mg clearance, and fractional clearance of Mg in horses fed diets with Mg content above and below National Research Council recommendations. Six horses were fed a reduced-Mg diet for 29 days followed by an Mg-supplemented diet for 24-days. Three horses were fed grass hay respectively (control group). The authors concluded that 24-hour urinary Mg-excretion was the most sensitive indicator of a reduced Mg intake in horses. However, determination of the fractional clearance of Mg by spot sampling can also be used conveniently to indentify magnesium deficient horses.
Keywords: hypomagnesemia; intracellular Mg; minerals; urine; retention test.
Stewart, A.J., Hardy, J., Kohn, C.W., Toribio, R.E., Hinchcliff, K.W. and Silver, B. 2004. Validation of diagnostic tests for determination of magnesium status in horses with reduced magnesium intake. American Journal of Veterinary Research 65: 422-430.
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